Amoebiasis

Summary

  • Entamoeba histolytica: trophozoites and cysts; faeco-oral transmission
  • Morphological identical but non-pathogenic Entamoeba dispar
  • Intestinal infection: asymptomatic – colitis – fulminant dysentery – amoeboma.
  • Amoebic colitis to be distinguished from bacillary dysentery, balantidiasis, colon cancer, Crohn’s disease, ulcerative colitis
  • Liver infection: Liver abscess with fever, liver pain, pus upon aspiration, leukocytosis, positive serology, abnormal ultrasound.
  • Liver amoebiasis to be distinguished from pyogenic abscess, cholangitis, cholecystitis
  • Occasionally perianal skin ulcers and other extra-intestinal locations
  • Treatment with nitro-imidazoles + contact amoebicides

Entamoeba histolytica Life Cycle (courtesy of CDC)